Daily THC exposure causes CB1 receptors to downregulate (decrease in number) and desensitize (reduce response). Within 2-4 weeks of regular use, the same dose produces noticeably less effect. The receptor system adapts.
Stop all cannabis use for 7 days minimum, 14 days for full reset. CB1 receptors upregulate within the first week. By day 10-14, sensitivity returns close to baseline. The first session post-break: start at 50% of your previous dose to avoid surprise.
If a full T-break feels impossible, try microdosing instead. 2.5mg edible every 2-4 hours during the workday, then a normal session at night. Studies suggest microdose patterns slow tolerance build vs continuous heavy use.
7 days minimum, 14 days for full reset. CB1 receptors upregulate within the first week; sensitivity returns close to baseline by day 10-14. Post-break first session: take 50% of your previous dose to avoid surprise from restored sensitivity.